Nei cellulose ether inoshandiswa zvakanyanya mumishonga yemishonga?

Mishonga yePharmacedical ndeyemhando yepamusoro uye adjuncts inoshandiswa mukugadzirwa uye kugoverwa kwezvinodhaka, uye chikamu chakakosha chekugadzirira mishonga yemishonga. Cellulose ether sekutorwa kubva kune zvakasikwa Polymer zvinyorwa, ane hunhu hwe biodelose, sodixpressl cellemose, methyl cellylsl cellyl celler Kukosha mune iyo pharmaceutical excividents. Parizvino, zvakawanda zvezvigadzirwa zveMubati weDhem

Pharmaceutical Exccividents Market Inogona Kukura

Mishonga yemishonga yePharmacience anotamba basa rakakosha mukusimudzira uye kugadzirwa kwekugadzirira kwemishonga. Semuenzaniso, pakugadzirira-kusunungurwa-cellerse ether uye mimwe polymer zvinyorwa zvevashandi vakaburitswa, kusunungurwa-kusunungura-firimu, resin zvinodhaka-zvinodhaka zvekusunungura uye kugadzirira kwemvura kunosunungurwa. Mune ino system, cellulose ether uye vamwe polymers vanowanzoshandiswa seyekutakura zvinodhaka kuti vadzore mwero wekubhadhara zvinodhaka mumuviri mune imwe nguva yakatarwa mukati meimwe nguva yekuzadzisa chinangwa chekurapa.

Zvinoenderana nehuwandu hweZhiyan Consulting neDhipatimendi Rakanyorwa, Mhando dzeUnited States (Mhando yepamusoro), mhando ichiri kuderera, China mishonga yeChinese. Zvinonzwisisika kuti iyo yepamusoro mishonga yekunyepedzera muChina mishonga yeGelatin Capsule, PVP

Nhanhatumarudzi ecellulose ethermukatiPharmaceutical Exccivients

Natural Cellulose Elkwa IS Alkalose Cellalose uye Etera Cellulose ether inoshandiswa zvakanyanya muPetroleum, zvekuvakisa, zvekuvakwa, mushonga uye minda yezuva nezuva, mishonga, mishonga-mishonga inopera munda yeindasitiri, ine kukosha kwakanyanya. Nekuda kwekunetseka kwakasimba, kugadzirwa kwemishonga yegiredhi cellulose ether kwakaoma zvakanyanya, zvinogona kutaurwa kuti mhando yezvigadzirwa zvegiredhi mishonga inogona kumiririra iyo technical simba re cellumose ether Bhizinesi. Cellulose ether inowanzo shandiswa seblocker, skeleton zvinhu uye zvakagadzirwa neyekudzima-sjeya microcapsule pairatiki zvinhu, zvakasarudzika-zvinoshamisa-zvinodhaka-zvinodhaka zvezvinodhaka zvekushandisa mumifananidzo.

Sodium carboxymethyl cellelose

Sodium CarboxyMethyl Cellerose (CMC-na) ndiyo hurukuro yakakura uye desage yekotoni marudzi kumba uye neyekotoni, CMC-NA irwo rudzi rweimwe raiwanzoshandiswa phamacecucums. In Inononoka (inodzorwa) gadziridzwa gadziriro, inowanzoshandiswa seyemufirimu emumiririri emidziyo yekudzora zvinodhaka uye mahwendefa ekusunungura zvishoma.

Pamusoro peSodium CarboxyMeymelm Cellemelose so mishonga yekunyora, Crosslinked Sodium carboxymelose inogona zvakare kushandiswa semishonga yemishonga. Crosslinked Sodium CarboxyMeylC Cellerose (CCMC-NA) ndiyo yakacheneswa mvura insolubelthethlem cellention Mumiriri wekuyambuka anogona kuve progressy glycol, succucinoc anhydride, maleic anydride uye adipic anydride. Crosslinked Sodium CarboxyMeym Carbolose inoshandiswa seyekupararira kwemapiritsi, makapu uye mapoka emuromo uye kuzvimba kuve nemhedzisiro yekusagadzikana, simba rayo rakanaka, simba rakasimba. Zvidzidzo zvakaratidza kuti dhigirii rekuzvitsvagedza sodium carboxym Carbolosel Cellever

Methyl cellulose

MetHyl Cellulose (MC) isingaoneki cellulose exherulose ether yakagadzirwa kubva kuCotton uye huni neayo neAffasization, chlomethane eriralization uye mamwe maitiro. Methyll Cellulose ine yakanakisa mvura solubility uye yakagadzikana mune pH range ye 2.0 ~ 13.0. It is widely used in pharmaceutical excipients, sublingual tablets, intramuscular injections, ophthalmic preparations, oral capsules, oral suspensions, oral tablets and local preparations. Mukuwedzera, mc inogona kushandiswa seHydrophilic Gel Chimiro Chakasimudzirwa, Gastric Solullapses Collatues Coating Zvinyorwa, Akasunungurwa-Akasunungurwa-Anodhaka Firm Stullents, nezvimwe.

Hydroxypruppyl methyl cellulose

HydroxyPropyl methyl methyl cellelose (HPMC) is nonitic cellulose ether yakagadzirwa kubva kuCotton uye huni neayo Izvo hazvina musoro, zvisingaravirire uye zvisina chepfu, zvine mwero mumvura inotonhorera uye mvura inotonhorera uye ine gelatinous mumvura inopisa. HydroxyPropyl methyl celler izimba remukati, madhiri uye mhando yemakore gumi nemashanu ari kukurumidza kuwanda kwemusha pamba uye kune imwe nyika yekunyora ine makore anoda kusvika makumi mashanu enhoroondo. Parizvino, HPMC application inonyanya kuratidzwa mune inotevera zvinhu zvishanu:

Imwe yakafanana neyekuchinjika uye yekuzvidza mumiririri. HPMC Semabhandi inogona kuita kuti zvinodhaka zvive nyore, uye mvura yayo inogona kuwedzera mazana emazana, saka inogona kuvandudza zvakanyanya kupaza kana kusunungurwa kwemahwendefa. HPMC ine yakasimba viscosity, yeiyo gadziriso yekrisimiki kana brittle yakaoma zvigadzirwa zvinhu zvinogona kusimudzira mavhiza etsiva, kugadzirisa kuumbwa kwayo. HPMC yakaderera viscosity inogona kushandiswa seyekuchinjika uye yekuregedza mumiririri, yakakwira viscosity chete seyekuchinjika.

Iyo yechipiri yakafanana nekudzora uye kudzorwa kwekuburitswa kwezvinhu zvekugadzirira zvemuromo. HPMC chinhu hydrogel chimiro chinowanzoshandiswa mukugadzirira-kusunungurwa kugadzirira. HPMC ine yakaderera viscosity level (5 ~ 50mpa ~ 50mpa ~ Mahwendefa ekusimudzira-akasimbisa. HPMC inogona kunyungudutswa muGastric Enterc Fluid, ine zvakanakira kudzvanywa, etrcomputer Carrial Gel chimiro chekugadzirira, uye chinoshandiswa mukugadzirira kugadzirira, uye kusunungurwa kugadzirira kugadzirira, kusunungurwa kugadzirira, kusunungurwa Mushonga wezvinodhaka mumiririri.

Yetatu, sefirimu rinobatanidza - kugadzira mumiririri. HPMC ine firimu yakanaka kuumba, inoumba yunifomu yefirimu, yakajeka, yakaomarara, kunyanya nekuda kwekunyorova, pamwe nacho seyakagoverwa kugadzikana kwemishonga, kudzivirira discoloration yefirimu. HPMC ine akasiyana siyana viscosity yakatarwa, yakadai sekusarudzwa kwakakodzera, inobatanidza mhando yemhando, kutaridzika kuri nani pane zvimwe zvinhu, zvinowanzoshandiswa zvakajairika zve2% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10% ~ 10%.

China chakaita seCapsule Capsule chezvinhu. Mumakore achangopfuura, nekubuda kweiyo denderedzwa remhuka pasi rese, zvichienzaniswa neGelatin Capsules, chirimwa capsules zvave mudhara mutsva wesisitiri yemishonga uye yechikafu. PFiza yakabudirira kubvisa HPMC kubva kune zvakasikwa zvirimwa uye zvakagadzirirwa VCaptm chirimwa capules. Kuenzaniswa neiyo tsika yegwenzi reGelalla capsules, chirimwa capules zvine zvakanakira kushandurwa kwakakura, hapana kuyambuka-kuunganidza maitiro ekuita uye akanyanya kugadzikana. Iyo yekuburitsa zvinodhaka inogadzika zvakagadzikana, kusiyana kwemunhu zvidiki, uye hazvibvi mushure mekusagadzikana mumuviri wemunhu, uye zvinogona kudzingwa mumuviri nemitezo. Panyaya yemamiriro ekuchengetedza, kuburikidza nehuwandu hukuru hwekuedza, makapu anenge asiri brittle pasi pemamiriro ezvinhu akaderera, uye maCapics emidziyo yakashata Nenjodzi dzevanhu dzemari dzemvura, pamwe nekuchinja kweruzhinji kwezvinodhaka pamba uye kunze kwenyika, iyo yemusika kudiwa kwezvirimwa capules ichakura nekukurumidza.

Shanu dzakaita semumiriri wemumiriri. Kumanikidzwa kwemvura kunowanzo shandiswa mumakirinari madhiri emhando, ayo ari hetegency kudzivirirwa masisitimu ezvibodzwa zvakashata mumvura inopararira midhiya. Kugadzikana kwegadziriro iyo inosarudza mhando yekugadzirira kwemvura yekugadzirira. HPMC Collodal Solution inogona kuderedza iyo yakasimba-yemvura nguva yekushushikana, kuderedza iyo yakasununguka simba rezvikamu zvakasimba, zvekuti nzira yekuparadzira yekuparadzira inowanzogadzikana, ndeyekumiriswa kwakanakisa. HPMC inoshandiswa seyakanyanya sedhese yeziso, uye zvirimo zviri 0.45% ~ 1.0%.

Hydroxyprupyl cellulose

HydroxyPropyl Cellulose (HPC) iri imwe chete nononic cellulose ether yakagadzirwa kubva kuCotton uye huni neayo HPC inowanzo kuvezwa mumvura pazasi makumi mana × uye nhamba huru yemolar sol sol. Zvivakwa zvayo zvine chekuita nezviri mukati mehydroxyprupyl uye degree rePolymerization. HPC inogona kuwirirana nemishonga dzakasiyana-siyana uye ine yakanaka inertia.

Yakaderera yakadzikira hydroxypropyl cellulose kuvandudza iyo cuctive maitiro.

Yakakwira yakakwira hydroxypropyl cellerose H-HPC ine firimu rakanakisa kuumba pfuma, iyo firimu yakawanikwa yakaoma uye yakasarudzika, uye inogona kufananidzwa neplasticze. Nekusanganisa nedzimwe unti-moisture coating vhiziri, basa remafirimu rinogona kuwedzerwazve, uye rinowanzoshandiswa seye firimu rinovhara zvinyorwa zvemahwendefa. H-HPC inogona zvakare kushandiswa seyakagadziriswa zvinhu kugadzirira mahwendefa ekusimudzira-masimba-masimba-masimba-ekuburitsa-masendimita uye maviri-denderedzwa mahwendefa.

HydroxytHyl Cellulose

Hydroxethyl Cellulose (HEC) ndeye imwe nonition cellulose ether yakagadzirwa kubva kukotoni uye huni neaxylene oxide etertification uye mamwe maitiro. Hec inonyanya kushandiswa seanotsigira, Colidal Privation mumiriri, anoparadzira, stabilizer, kumiswa mumiriri, firimu rekugadzira mumiriri uye rakaburitswa-rekuburitsa-mune zvekurapa mumunda wekurapa. Inogona kushandiswa mumabhadharo emuchero emunharaunda, ointions, madonhwe emuromo, emuromo wemuromo, mahwendefa akasimba, mahwendefa nemamwe mafomu. HydroxytHyl Cellulose yakabatanidzwa muUnited States Pharmacoeia / United States National Formulary uye European Pharmacoeia.

Ethyl Cellulose

Ethyl Cellulose (EC) ndeimwe yemvura inonyanya kushandiswa-insoluble cellulose inobva. EC isiri-ine chepfu uye yakagadzikana, kusakwana mumvura, acid kana alkali mhinduro, methanol uye methanol uye mamwe organic sol. Zvakajairika solventts ndeye toluene / ethanol musanganiswa we4/1 nehuremu. EC ine zvakawanda zvinoshandiswa mune zvinodhaka-zvinodhaka Kugadzirira kwekusunungura zvishoma nezvishoma kaputi; Inogona zvakare kushandiswa zvakanyanya seyakakura zvinhu kugadzirira kupararira kwakasimba. Iyo inoshandiswa zvakanyanya mune yemishonga tekinoroji seye firimu inogadzira chinhu uye inodzivirira yekuvhara, pamwe neyekuchinjika uye inochengetera. Sekuratidzira mahwendefa, zvinogona kuderedza kunzwa kwemahwendefa kuti uzvininipire uye kudzivirira zvinodhaka kubva mukukanganiswa nekunyoroveswa uye discoloration. Inogona zvakare kuumba chinononoka-chinonamira chinonamira uye chengetedza iyo polymer ine microcapsules, kuitira kuti iyo mushonga unodhonza unogona kusunungurwa nguva dzose.

Isu tichabvisa pakati - uye kuderera-kumagumo-ekupedzisira application uye kukurudzira shanduko uye kusimudzira

Kuti upedze kumusoro, iyo mvura-sodium carboxymelose, metdroxypressl metherlose, sololuxpressl cellulose Formers, capsule capsule zvinhu uye yakamiswa rubatsiro inoshandiswa mune iyo mishonga yemishonga yekuenzanisa. Kutarisa nyika, makambani mazhinji ekunze-emarudzi ekunze (Japan shin-etu, United States dow wolf yeMapermace muChina, kana kuwedzera kugadzirwa, kana kuwedzera mari yekudyara mumunda uyu mumunda uyu. Dow yakazivisa kuti ichabvisa pfungwa dzayo pane mafomu, zvinongedzo uye zvinodikanwa zveMusika weChinese emishonga, pamwe nekuedza kwayo kuunza kutsvagisa padyo nepamusika. Dow's Cellulose Chikamu uye Ruvara rwakagadzika mubatanidzwa wepasi rose wekudzorwa Ashland ine zvivakwa muBeijing, Tianjin, Shanghai, Nanjing, Changzhou, Kunshan naJiangmen, uye akaisa mari mune matatu ekutsvaga tekinoroji kuShanghai uye Nanjing.

Maererano newebhusaiti yeChina Cellulose Erth Association, muna 2017, iyo yekubudira kweCellulose ether yaive 373,000 matani ematani, uye vhoriyamu yekutengesa yaive makumi matatu nemakumi matatu ematani. Muna 2017, iyo chaiyo yekutengesa yeIonic cmc yaive makumi matatu nematanhatu matani, kumusoro 18,61% gore pagore, uye zvevasina-ionic cmc yaive matani gumi nemaviri, kumusoro 8.2% gore pagore. Zvigadzirwa zvisiri zveIonic mukuwedzera kune HPMC (HPMC (phmaceutical), HPMC (HPMC (HPMC (HPMC (HPC, HPC uye zvichingodaro ichivhara maitiro nekuwedzera uye kuwanda. Domestic Cellulose genera yakakurumidza kupera kweanopfuura makore gumi, kubuda kwave kutanga nyika

Various Cellulose Enterpriise kumba uye kunze kwenyika, zvakanyanya mukusimudzira kwezvigadzirwa zvepasi rose, nekuwedzera kusimudzira kwechigadzirwa