Hydroxypropylmethylsellose (HPMC) ndeye polulose-yakavakirwa polymer inoshandiswa zvakanyanya mumunda wemishonga, kunyanya mukuvandudza kwehydrophilic matrix matrix matrix matrix masystem. Iyi masisitimu matrix ndeyekutsoropodza kudzora kusunungurwa kweiyo inoshanda mishonga mishonga (APSI) mune yakadzorwa uye yakasimba maitiro. HPMC inowanikwa mune dzakasiyana-siyana vhiza, uchibvumira mafuro emishonga kuti ugadzirise zvinhu zveMatrix system kune zvakananga zvinodhaka zvinodhaka.
1. Nhanganyaya yeHPMC Polymer
Tsanangudzo uye chimiro
HPMC ndeye semi-synthetic yemvura-soluble polymer inotorwa kubva ku cellulose. Iyo ine 2-hydroxypruppropyl uye methyl inodzokorora zvikamu zvakabatanidzwa kune cellulose backbone. Dhigirii rekutsiva kwemapoka aya rinobata zvivakwa zveHPMC, kusanganisira yayo solubility, viscosity, uye kugona kugona.
2. Basa mune mishonga gadziriso
HPMC ine zvakanakira zvakati wandei seyenzi muzvimiro zvemishonga. Yayo hydrophilic yemasikirwo anoita kuti zviite kuti zviite kushandiswa muHydrophilic Matrix masisitimu, vachiumba chimiro cheGEL Ichi chimiro chinodzora kusunungurwa kwemushonga, kupa zvinogadziriswa uye kwenguva refu-maratidziro ekuraira.
3. Shanduko muViscosity Giredhi
Kukosha kweViscosity
Viscosity iri paramende inofungidzirwa mune yemishonga mafomu uchishandisa HPMC. Iyo inosarudza maitiro ekuyerera, kusununguka kwekugadzirisa, uye kusunungura hunhu hwemushonga kubva kune matrix system. Mavara akasiyana eHPMC ane zvisizvo visikoka, uye maFlogulators anogona kufadza-tune izvi zvivakwa zvichienderana nezvinodiwa zvezvinodhaka uye zvinodikanwa kuburitsa chimiro.
Viscosity Giredhi Sarudzo Yekushandisa
Iyo sarudzo yeHPMC viscosity giredhi inoenderana nezvinhu zvakadai sekudhaka salubility, yaunoda kuburitswa chiyero, dosage fomu, uye maitiro ekugadzira. Gadzirisa viscosity mamakisi angave akakodzera kuti uwedzere kusunungurwa zvinodhaka zvinodhaka, nepo yakakwira viscosity mamakisi anopa kusunungurwa kwakasimba.
Recipe Shanduko
Iko kuwanikwa kwehuwandu hwehuwandu hwemakwenzi anovandudza mafomu ekugadzira mafomu ekugadzira mukugadzira mishonga yemishonga yemishonga. Uku kuchinja kwakakosha kuti ugone kugara zvakasiyana zvinodhaka zvinodhaka uye simbisa iyo yekurapa kushanda kwechigadzirwa chekupedzisira.
4. Mhedzisiro pane zvinodhaka kuburitswa
Kudzoserwa kwezvinodhaka kuburitswa
HPMC matrix masisitimu anoshanda pane iyo nheyo yehydration uye gel kuumbwa. Kana matrix achiuya mukubatana nemvura, inoerera uye inoumba guruva rakakomberedza mishonga yemishonga. Mushonga wacho unosunungurwa kuburikidza nehasha uye kugura kweiyo gel layer. Kuchinja iyo viscosity yeHPMC inobvumira zvakanyatsogadziriswa kweiyo chiyero uye nguva yekuburitswa kwezvinodhaka.
Yakaburitswa Kuburitswa Kugadzirira
Yakakwira viscosity mamakisi eHPMC inowanzoshandiswa mukuvandudzwa kwekusunungurwa-kwakasunungurwa. Aya mafambiro akagadzirirwa kuburitsa rubatsiro rwezvinodhaka, kuderedza dosing frequency uye kugadzirisa kutevedzera murwere.
5.MuRiting Rekutarisira
Kugadzirisa Matambudziko
Kusarudza iyo yakakodzera HPMC viscosity giredhi inokurudzirwa zvakare nekugadzira kufunga. Mapamusoro ekusvitsa mamakisi anogona kugadzira matambudziko panguva yekugadzirisa, sekuti yakawedzera kusanganisa nguva uye zvingangoita zvishandiso zvemidziyo. Vagadziri vanofanirwa kurova chiyero pakati pekuzadzisa iyo inodiwa inodhaka profiles
Kuwirirana nevamwe vaenzanisa
HPMC inowanzoshandiswa mukubatanidzwa pamwe nezvimwe zvakanaka kuti uwane zvibodzwa zvekuumbwa. Kuenderana kweiyo yakasiyana viscosity mamakisi nedzimwe chete maExcividents organte kiyi yekufunga kuti ive nechokwadi chekugadzikana uye kuita kweiyo yekupedzisira dosi fomu.
Kutevedzera kufunga kutevedzera nemirairo
Kuumbwa kwezvinodhaka kunofanira kusangana nemataurire ekutonga, uye kushandiswa kweHPMC hakuna kusarudzika. Hpmc viscosity mamakisi anofanirwa kusarudzwa mukuteerana nezvinowanzoita zvinodiwa uye nhungamiro kuti ive nechokwadi chekuchengetedza, kushanda uye kunaka kweiyo mishonga yechechi.
HPMC Polymers inotamba chinzvimbo chakakosha mukuvandudzwa kwehydrophilic matrix masisitimu ekudzora zvinodhaka mukugadzika kwemishonga yemishonga yemishonga. Kuwanika kwemakiromita akasiyana eViscosity kunopa mafungidziro ekutenderera kune tailor zvinodhaka zvekusunungura profiti Kusarudzwa nokungwarira kwegiredhi rakakodzera viscosity rakakosha kuzadzisa basa raunoda paunenge uchinyorera gadzira uye yekuzvidzora pfungwa. Sezvinodhaka zvinodhaka uye kukura kunoenderera mberi nekufambira mberi, HPMC inogona kuramba ichitamba basa rinokosha mukugadzirwa kwevakadzvanywa uye vane hushamwari-hushamwari zvinodhaka.
Kutumira Nguva: Kukadzi-19-2025