Hpmc inokanganisa sei zvigadzirwa zvetsiva?

HydroxyPropyl methylcellose (HPMC) ipurusi-soluble polymer inowanzo shandiswa mune indasitiri, mushonga uye chikafu. Imwe yemabasa makuru eHPMC mune dzakasiyana zvigadzirwa ndeyekugadzirisa zvevasokisi, izvo zvinowanikwa kuburikidza neyako molecular chimiro uye kuwirirana nemanyowa (kazhinji mvura).

1. Molecular chimiro cheHPMC uye zvarinoita pane viscosity
HPMC inoenderana neCellulose Backbone ine methxy uye hydroxypruppropyl subsituents. Chaiyo cellulose chain dzinotakura huwandu hwakakura hwemapoka ehydroxyl (-OOOH), izvo zvinogona kuumba hydrogen zvisungo zvine mamorekuru, nekuwedzera kuwedzeredza visikopa. Iyo hydroxypruppropyl uye nzira dzinotsiva muHPMC MOLECULE inokanganisa hukama hwayo uye solubility nemvura. Mumvura, iyo HPMC molecular cheni inogona kuitika uye inotora huwandu hukuru hwemvura, nekudaro achiwedzera visikopa yemhinduro.

Mhando dzakasiyana dzeHPMC rinoratidza zvakasiyana zvevascosity hunhu nekuda kwemadhigiri avo akasiyana edhixx uye hydroxyprupropyll substitution. Kazhinji, HPMC ine mwero wepamusoro we hydroxypresspl Naizvozvo, iyo moleky chimiro cheHPMC ine zvakananga kukanganisa pane yayo yekuwedzera-inowedzera maitiro.

2. Dissolution hunhu uye viscosity yeHPMC
HPMC ine yakanaka mvura solubility, iyo inoiita kuti iite zvakanyanya kuwedzera visikoka mumvura mhinduro. Mumvura, maketani ematehwe eHPMC about mvura uye gadzira iyo yakawedzera network network chimiro, zvichikonzera kuderera kweiyo fluidity yeiyo mhinduro uye kuwedzera kweViscosity. Uku kudzvinyirira kwekunyungudza idanho-ne-nhanho maitiro, uye tembiricha nePH zvine hunhu hwakakosha pazviri. Kazhinji, HPMC inodonha nekukurumidza pakudziya kwakadzika, asi viscosity yayo inowedzera nekuwedzera kupisa. Naizvozvo, yakakwira tembiricha yekudzvinyirira mukati meimwe huwandu, iyo yakakura viscosity yemhinduro.

Iyo solubility yeHPMC inoenderana zvakare nePP kukosha kwesium. Mukusarerekera kune isina kusimba alkaline range, Hpmc inodonha zviri nani uye inowedzera zvavakaita; Ndichiri pasi pemamiriro ekunze akasimba kana alkaline mamiriro, iyo solubility uye visucosity yeHPMC inotorwa. Naizvozvo, mune zvakasiyana zvigadzirwa, kugona kweViscosity kugona kweHPMC zvakare kunodawo kufunga nezve ph kukosha kweiyo svikiro.

3. Mhedzisiro yeHPMC yekuvhara pane viscosity
Iko kusangana kweHPMC ndechimwe chezvinhu zvakakosha zvinokanganisa viscosity. Sezvo kusangana kweHPMC inowedzera, iyo molecular keteni network yakaumbwa mumhinduro inova denser uye viscosity inowedzera zvakanyanya. Pakusangana, kudyidzana pakati peHPMC molecular ketani isina kusimba, uye visikopa yemhinduro haina kuchinja zvakawanda. Nekudaro, apo iyo HPMC yekuvhara inosvika kune imwe nhanho, iyo yekubatanidza uye kupinda pakati pemaketani manyoro kuchaita kuti vhiza riwedzere kuwedzera.

Kuedza kunoratidza kuti kana iko kusangana kweHPMC kuri mukati meimwe renji, viscosity yayo inowedzera muzvikamu zvakananga pakukoshesa. However, when the concentration is too high, the rheological properties of the solution will change, showing pseudoplasticity or thixotropy, and the viscosity decreases with the increase of shear rate. Naizvozvo, mune zvinoshanda zvinoshandiswa, huwandu hweHPMC zvakawedzerwa zvinoda kuti zviitwe zvine musoro zvichienderana nezvinodiwa chaizvo kuti zviitwe kwazvo zvevisa.

4. Mhedzisiro yeiyo molecular uremu pane viscosity
Iyo molecular uremu hweHPMC zvakare chakakosha pane kusimbisa zvavakaita. Kazhinji, iyo yakakura iyo smecular uremu hweHPMC, yakakwira viscosity yemhinduro yayo. Izvi zvinodaro nekuti HPMC ine hupamo hombe inorema inogona kuumba mapopoma manyorerwo uye zvimwe zvakaoma midziyo, nekudaro zvichitadzisa iyo fluidity yemhinduro uye kuwedzera iyo viscosity. Naizvozvo, HPMC ine akasiyana ma molecular zviyero zvinogona kushandiswa kugadzirisa zvinodiwa zvevatenzi zvezvigadzirwa zvakasiyana.

Mune zvimwe zvekushandisa, kusarudza iyo yepamusoro molecular uremu hpmc inogona kuvandudza zvakanyanya kuwirirana kwechigadzirwa, chakadai sedhiziri rekuvaka; Ndichiri mune zvimwe zvekushandisa, senge munda wemishonga, yakaderera molecular uremu hpmc ingangoda kusarudzwa kuitira kuti igadzirise chiyero chekuburitsa kana kugadzirisa kuravira.

5. Mhedzisiro yekupisa pane viscosity yeHPMC Solution
Iyo viscosity yeHPMC inoshandura zvakanyanya nekushisa tembiricha. Kazhinji, iyo viscosity yeHPMC Soluolure inoderedza kupisa kwakanyanya. Izvi zvinodaro nekuti tembiricha yakakwira inoparadza iyo hydrogen zvisungo pakati peHPMC mamorekuru uye inoderedza mwero wekupinda kwemaketani emanyorerwo, nekudaro achideredza zviso zvemhinduro. Nekudaro, mune zvimwe zviitiko zvakakosha, viscosity yeHPMC inogona kuwedzera mukati meimwe tembiricha yekupisa, iyo ine hukama zvakanyanya neyakaomarara uye mamiriro ekugadzirisa.

Pakudziya kwakadzika, visikopa yeHPMC mhinduro yakakwira uye kufamba kwemaketani anonyadziswa kunodzorwa. Ichi chivakwa chinoita kuti zviite zvakanaka mune zvekushandisa uko viscosity yechigadzirwa pachiyero kupisa kunoda kuwedzerwa.

6. Mhedzisiro yeShear Rate pane viscosity yeHPMC
HPMC mhinduro dzinowanzo kuratidzira shear yekufungidzira maitiro, kureva kuti, viscosity inoderera nekuwedzera shear rate. Pamari yakaderera shear, iyo network network yeHPMC molecular keteni yakakwana, inokanganisa fluidity yemhinduro, nekudaro ichiratidza yakakwira viscosity. Nekudaro, pamitero yakakwirira shear, iyo intanglement uye kuunganidzwa-kuunganidzwa kwemaketani anonyungudutswa anoparadzwa, uye visikoka vanoderera. Ichi chivakwa chinoshandiswa zvakanyanya mumaindasitiri akadai sekushandisa kwekuvaka, pendi uye hukuru, uye zvinogona kuvandudza kuiswa kwezvigadzirwa panguva yekuvaka.

7. Mhedzisiro yekuzvidzwa kwekunze
Mune akawanda mashandisirwo, HPMC inowanzoshandiswa pamwe chete nezvimwe zvinowedzera. Mhando dzakasiyana dzekuzvidzwa, dzakadai semaronda, surfers ands nevamwe polymers, ichakanganisa viscosity yeHPMC. Semuenzaniso, mamwe munyu anowedzera anodzikisa zveview mhinduro dzeHPMC nekuti munyu unonetsekana nekudyidzana pakati peHPMC ngetani uye kuparadza iyo hydrogen bond network yakaumbwa. Dzimwe nhaurwa dzinogona kushanda synergistically neHPMC kuti uwedzere huwandu hwakawanda hwemhinduro.

Semunhu akashandiswa akashandiswa zvakanyanya, hpmc's elpc's viscosity inonyanya kuwanikwa kuburikidza nemhedzisiro yemasangano manyoro, solecular uremu, uye zvinhu zvekunze zvakadai sekushisa, Shear rate uye zvinowedzera. Nekugadzirisa zvine musoro idzo parmet, kudzora chaiko kwechigadzirwa viscosity inogona kuwanikwa kuti isangane nezvinodiwa zveminda yakasarudzika yekushandisa.