HyproMellose (HPMC) is cellulose inobviswa iyo yakashandiswa zvakanyanya muindasitiri yemishonga nekuda kwezvinhu zvakanaka zvechiratidzo uye biocomputer. Nzvimbo dzayo huru dzekushandisa dzinosanganisira kubiridzira mabhedheni, disintegraphs, inovhara zvinhu, dzakasimbiswa-dzakaburitswa-vamiriri, uye kugadzirira kwemvura zvinodhaka uye geri.
1. Binders
Mukugadzira piritsi, HPMC sekuwedzera kunogona kusimudzira simba rekusunga kwezvinodhaka, zvichivaita kuti vagadzire mapiritsi akagadzikana panguva yekubatwa. HpMC Binder ane zvinotevera zvinotevera zvakanakira:
Simbisa Simba Simba: Iyo viscous network yakaumbwa neHPMC muHPMC muHPMC muHPMC muHPMC iri kunatsiridza Simba rekusimba kwehwendefa uye kuderedza njodzi yekupatsanurana nekuparadzanisa.
Kuvandudza Uwandu: Nekuda kwekunakidzwa kwayo solubility mumvura, HPMC inogona kugoverwa pamusoro pezvikamu zvevakarongedzwa zvinodhaka mune yega yega piritsi.
Kugadzikana: HPMC inoratidza kukanganisika kwakanaka pasi pe tembiricha yakasiyana uye manyoro emamiriro ezvinhu, uye inogona kuchengetedza chimiro piritsi apo kuve kushoma kutapwa kune zvinoitwa zvakatipoteredza.
2. Disintegrants
Basa rekuparadza ndere kugadzira mahwendefa ekuparadzira nekukurumidza mushure mekusangana nemvura kusunungura zvinodhaka. HPMC inogona kuita zvinobudirira kukurudzira piritsi yekuparadzira nekuda kwekuzvimba kwayo kwekuzvimba kwayo:
Hydration Kuzvimba: Kana HPMC ichisangana nemvura, ichakurumidza kutora mvura uye ichipfuudza, ichikonzera chimiro chemubiriya kuti chibvise, nekudaro uchisunungura zvinodhaka.
Kugadzirisa nguva yekuparadzira: Nekugadzirisa iyo yeHPMC, iyo nguva yekuvharidzira yematafura inogona kudzorwa nenzira kwayo kuti isangane zvinodiwa zvinoshamisa zvezvinodhaka zvakasiyana.
3. Kubatanidza zvinhu
HpMC inoita basa rakakosha mukukwira piritsi. Kugona kwayo kwefirimu-kuumba kugona uye kudzivirira zvinokanganisa zvinodhaka zvinoita kuti ive yakanaka yekubatanidza zvinhu:
Kuzviparadzanisa: HPMC Kubatanidza kunogona kukanganisa zvinyorwe zvinoshanda mumativi kubva kunharaunda yekunze kudzivirira maunzi, oxidation uye Photolysis.
Kuvandudza Chitarisiko: HPMC Coating inogona kupa yakatsiga yekunze pamusoro, kuvandudza kutaridzika uye kusununguka kwekumedza mahwendefa.
Kugadzirisa kuburitswa kwezvinodhaka: kuburikidza neakasiyana HPMC mafomu uye inokatyamadza, kusunungurwa kusunungurwa kana kusunungurwa kusunungurwa kunogona kuwanikwa.
4. Zvinosimbiswa-zvakaburitswa vamiririri
Hpmc inozoshandiswa zvakanyanya mukugadzirira-kusunungura gadziriro. Kuburikidza neGel Barrier iyo mafomu, inogona kunonoka kuburitswa kwezvinodhaka uye kuwana kurapwa kwenguva refu:
Gel Barrier: Mune mahedheni emvura, HPMC inodonha uye inoumba viscous gel, iyo inogona kudzora chiyero chekuburitsa chemushonga.
Kusunungurwa kwakasimba: Iyo viscosity uye yekuvhara yeHPMC inogona kuve chaiyo inodzorwa kuti iwane kusunungurwa uye kufungidzira kusunungurwa kwezvinodhaka.
Yakadzora mishonga freation
5. Kugadzirira kwemvura uye Gels
HPMC inoita basa rakakosha seanoshamwaridzana uye stabilizer mumvura gadziriro uye gels:
Kuita kwakasimba: HPMC inoumba yunifomu mhinduro yemvura mumvura, iyo inogona kuwedzera visikopa yekugadzirira kwemvura uye kugadzirisa kumiswa kumiswa.
Simbisa maitiro: HPMC inogona kuchengetedza visikoka yakagadzikana pasi pemamiriro akasiyana-akasiyana-siyana, ayo anobatsira kusimbisa zvinodhaka zvinodhaka uye kudzivirira kufungidzira uye kugadzikana.
6. Zvimwe zvinoshandiswa
HPMC inoshandiswawo kugadzirira kugadzirira kweOPHTRIMIC
OPHTALMIC ERETRATIONS: HPMC inoshandiswa seyakagadzirwa mumisodzi yemisodzi uye ziso rinodonha kudzoreredza zvinorwadza zviratidzo zveziso.
Kugadzirira kweNALL: Semukati mani muNASAL Sprays, HPMC inogona kuwedzera nguva yekuchengetwa kwemishonga mumhino yemhino.
Kugadzirira kwepamusoro: HPMC kunogona kuumba firimu rekudzivirira mumamiriro ekugadzirira kuti ubatsire zvinodhaka kugara paganda refu.
Semunhu anoshanda excilient, hydroxyprupyl methylcellose anoshandiswa zvakanyanya muindasitiri yemishonga yemishonga. Mabasa aro akawanda mukugadzira piritsi kugadzira, kuunganidza, gadziriro-yekugadzirira-gadziriro, gadziriro dzemvura uye gles dzinokosha kuvandudza kunaka uye kugadzikana kwekugadzirira zvinodhaka. HPMC yave iri chinhu chakakosha uye chakakosha zvinhu muindasitiri yemishonga nekuda kweiyo yakanakisa biocomputilation uye inoshanda zvivakwa. Mune ramangwana, nekukura kusingaperi kwehunyanzvi hwemishonga, tarisiro yekushandisa yeHPMC mukutsvaga zvinodhaka uye kukura uye kugadzirwa kwemaitiro kuchave kwakakura.
Kutumira Nguva: Kukadzi-17-2025